The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Editorial
PreviousPrevious
Volume 332:529-530 February 23, 1995 Number 8
NextNext

Minimizing the Risks Associated with the Prevention of Poliomyelitis

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited

More Information
-PubMed Citation
The global eradication of poliomyelitis has been targeted as a goal for the year 2000 by the World Health Organization,1 and naturally occurring poliomyelitis has already been eradicated from the Americas.2 Yet the occasional occurrence of paralytic poliomyelitis in association with the use of the trivalent oral poliovirus vaccine — either in vaccine recipients or in others who are in contact with recipients — remains a vexing problem. The basis for this rare breakthrough disease lies in the potential of the live attenuated virus in the vaccine to revert to increased virulence within the human gastrointestinal tract. Although such genetic . . . [Full Text of this Article]

References



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.