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Previous Volume 332:612-613 March 2, 1995 Number 9 Next

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To the Editor: Chevron and coworkers (Oct. 27 issue)¹ reported the absence of immunostaining for utrophin on the surface of muscle fibers in an unidentified muscle from a boy with a form of muscular dystrophy who died at the age of 15 years. An absence of immunostaining for dystrophin was also observed. These data were interpreted as being indicative of the absence of the expression of both dystrophin and utrophin, possibly because of the absence of a common intramembranous (plasmalemmal) protein that binds both dystrophin and utrophin. The authors correctly point out that in normal skeletal muscle, utrophin is . . . [Full Text of this Article]

References

Related Letters:

Absence of Dystrophin and Utrophin in a Boy with Severe Muscular Dystrophy
Chevron M.-P., Echenne B., Demaille J.
Extract | Full Text  
N Engl J Med 1994; 331:1162-1163, Oct 27, 1994. Correspondence

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