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Previous Volume 333:56-57 July 6, 1995 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Renal cysts look innocent enough. When they occur alone, as they commonly do in adults over the age of 50 years, they do no harm. The handiwork of the aging process, some would have you believe. But when they appear in the kidneys in large numbers, as in patients with autosomal dominant polycystic kidney disease, renal cysts can lead to the destruction of renal parenchyma and to chronic renal failure. Autosomal dominant polycystic kidney disease is the most common monogenic disorder that is potentially fatal. Each year nearly a billion dollars is expended in the treatment of patients with the . . . [Full Text of this Article]

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• Puri, S., Magenheimer, B. S., Maser, R. L., Ryan, E. M., Zien, C. A., Walker, D. D., Wallace, D. P., Hempson, S. J., Calvet, J. P. (2004). Polycystin-1 Activates the Calcineurin/NFAT (Nuclear Factor of Activated T-cells) Signaling Pathway. J. Biol. Chem. 279: 55455-55464 [Abstract] [Full Text]  
• Ali, S. M., Wong, V. Y., Kikly, K., Fredrickson, T. A., Keller, P. M., DeWolf, W. E. Jr., Lee, D., Brooks, D. P. (2000). Apoptosis in polycystic kidney disease: involvement of caspases. Am. J. Physiol. Regul. Integr. Comp. Physiol. 278: R763-R769 [Abstract] [Full Text]