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Correspondence
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Volume 333:669-670 September 7, 1995 Number 10
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Estrogen, Lipid Oxidation, and Body Fat

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To the Editor: Oral estrogen treatment is associated with weight gain and often with the perception on the patient's part of increased adiposity.1 Evidence of increased body fat is lacking, and the possible mechanism involved is not known. We report the results of a study in a tall young woman, which suggest that estrogen decreases lipid oxidation and increases body fat.

The patient was a 19-year-old woman with ovarian agenesis treated with 60, then 100, and then 200 µg of ethinyl estradiol per day, with each dose given for one month, which resulted in epiphyseal closure. Treatment with an oral . . . [Full Text of this Article]

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