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Previous Volume 333:724-726 September 14, 1995 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In this issue of the Journal, Pathmanathan et al.¹ add a new dimension to the etiologic link between Epstein–Barr virus (EBV) infection and anaplastic nasopharyngeal carcinoma. Genetic and environmental factors have also been implicated in nasopharyngeal carcinoma.² In southern Chinese and some North African and Native American populations, it is a common cancer that causes substantial morbidity and mortality, even among young people. Although the carcinoma usually responds to radiotherapy, recurrences are frequent and difficult to treat.

A close association between EBV and nasopharyngeal carcinoma was previously established by the following findings: the presence of EBV DNA, RNA, and proteins . . . [Full Text of this Article]

References

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• Voo, K. S., Fu, T., Wang, H. Y., Tellam, J., Heslop, H. E., Brenner, M. K., Rooney, C. M., Wang, R.-F. (2004). Evidence for the Presentation of Major Histocompatibility Complex Class I-restricted Epstein-Barr Virus Nuclear Antigen 1 Peptides to CD8+ T Lymphocytes. JEM 199: 459-470 [Abstract] [Full Text]  
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• Horikawa, T., Sheen, T.-S., Takeshita, H., Sato, H., Furukawa, M., Yoshizaki, T. (2001). Induction of c-Met Proto-Oncogene by Epstein-Barr Virus Latent Membrane Protein-1 and the Correlation with Cervical Lymph Node Metastasis of Nasopharyngeal Carcinoma. Am. J. Pathol. 159: 27-33 [Abstract] [Full Text]  
• Posner, M. R., Cavacini, L. A., Upton, M. P., Tillman, K. C., Gornstein, E. R., Norris, C. M. Jr. (1999). Surface Membrane-expressed CD40 Is Present on Tumor Cells from Squamous Cell Cancer of the Head and Neck in Vitro and in Vivo and Regulates Cell Growth in Tumor Cell Lines. Clin. Cancer Res. 5: 2261-2270 [Abstract] [Full Text]  
• Fingeroth, J. D., Diamond, M. E., Sage, D. R., Hayman, J., Yates, J. L. (1999). CD21-Dependent Infection of an Epithelial Cell Line, 293, by Epstein-Barr Virus. J. Virol. 73: 2115-2125 [Abstract] [Full Text]  
• Moore, P. S., Chang, Y. (1998). Kaposi's Sarcoma-Associated Herpesvirus-Encoded Oncogenes and Oncogenesis. J Natl Cancer Inst Monogr 1998: 65-71 [Abstract] [Full Text]