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Previous Volume 333:940-941 October 5, 1995 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The suggestion by Krolewski et al. (May 11 issue)¹ that there is a threshold value for glycosylated hemoglobin above which the risk of microalbuminuria abruptly increases has important implications for the treatment of patients with insulin-dependent diabetes mellitus (IDDM). In their review of previous studies, the authors failed to mention the EURODIAB IDDM Complications Study² involving 3250 patients (twice the size of their study), in which the risk of microalbuminuria increased with worsening glycemic control with no evidence of a threshold,² even after the patients were grouped according to the duration of IDDM, as was done by . . . [Full Text of this Article]

References

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