Expert panels in the United States and Europe have reinforcedguidelines on lowering cholesterol as one of the fundamentalpreventive measures to reduce mortality from coronary heartdisease.1,2 Last year the report of the Scandinavian SimvastatinSurvival Study strengthened the evidence on which the guidelineswere based, demonstrating a survival benefit from lowering cholesterolwith simvastatin in patients with coronary disease.3 One remainingquestion has been whether aggressive cholesterol lowering inpersons without overt coronary heart disease will result insimilar benefits, without increasing the risk of noncardiacmortality. Another problem has been to find effective methodsfor lowering cholesterol . . . [Full Text of this Article]
References
Related Letters:
Prevention of Coronary Heart Disease with Pravastatin
Rogers S., Samani N. J., de Bono D. P., Davis D. R., Shepherd J., Cobbe S. M., Ford I., The West of Scotland Coronary Prevention Study Group , Pedersen T. R.
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N Engl J Med 1996;
334:1333-1335, May 16, 1996.
Correspondence
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