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Correspondence
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Volume 333:1359-1360 November 16, 1995 Number 20
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Doxorubicin-Induced Cardiotoxicity

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 by Lipshultz, S. E.
To the Editor: The study by Lipshultz et al. (June 29 issue)1 has confirmed the results of an earlier study of 150 survivors of cancer who were treated at the Children's Hospital of Philadelphia.2 Our study, published in 1993, analyzed abnormalities in either maximal cardiac output, indexed according to body-surface area, or the ejection fraction, as measured by resting or exercise gated nuclear angiography, in patients who had received anthracyclines and who had not been treated for at least one year. We omitted patients who received spinal radiation, since such treatment may also damage the heart.3 We found that after . . . [Full Text of this Article]

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