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Editorial
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Volume 333:1414-1415 November 23, 1995 Number 21
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Vitamin A and Birth Defects — Continuing Caution is Needed

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Vitamins are essential to good health, yet the consumption of excessive amounts of some vitamins, particularly A and D, can lead to toxicity. In this issue of the Journal, Rothman et al.1 add to a body of evidence suggesting that the consumption of too much vitamin A by pregnant women may cause birth defects. On the other hand, the Public Health Service recommends that all women capable of becoming pregnant should consume 0.4 mg of folic acid daily to prevent the serious and common birth defects spina bifida and anencephaly.2,3,4 It is important for women and their physicians not to . . . [Full Text of this Article]

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