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Previous Volume 333:1502-1503 November 30, 1995 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Lang, C. C. Related Article by Lang, C. C.

To the Editor: The study by Lang and colleagues (July 20 issue)¹ is provocative but lacks two important control observations. First, as compared with the white subjects, the black subjects had markedly attenuated forearm blood-flow responses to isoproterenol yet similar increases in regional norepinephrine spillover. Hyperresponsiveness to the -adrenergic effects of endogenous norepinephrine is therefore at least as likely an explanation of the findings as hyporesponsiveness to -adrenergic stimulation by isoproterenol. No mention is made of this possibility; a direct infusion of norepinephrine or phenylephrine would easily settle the issue.

Second, since regional norepinephrine spillover is heavily dependent on blood . . . [Full Text of this Article]

References

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