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Correspondence
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Volume 333:1782-1783 December 28, 1995 Number 26
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Early Treatment of HIV Infection

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 by Kinloch-de Loës, S.
To the Editor: In an editorial on the studies of early treatment of human immunodeficiency virus (HIV) infection by Kinloch-de Loës et al.1 and Volberding et al.,2 Dr. Ho (Aug. 17 issue)3 cites a study showing that the plateau concentration of viral RNA after primary HIV type 1 (HIV-1) infection predicts the clinical outcome. He suggests that "treatment at the time of seroconversion may lower the initial viral plateau (`set point') and thereby improve the subsequent clinical course." Kinloch-de Loës et al. state that "the administration of antiviral therapy at the time of primary HIV infection is intended to decrease . . . [Full Text of this Article]

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