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Correspondence
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Volume 333:254-255 July 27, 1995 Number 4
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Interval Cytoreduction in Ovarian Cancer

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To the Editor: The article by van der Burg et al. (March 9 issue)1 on debulking surgery after induction chemotherapy raises some important issues. The authors state that the morbidity associated with a second operation was similar to that associated with a primary surgical procedure. This means a doubling of morbidity in those assigned to this arm of the study, and the impact on quality of life (and cost effectiveness) must be balanced against the six-month improvement in median survival rates. It will be interesting to learn the actual five-year survival rate in both arms, and we hope the authors . . . [Full Text of this Article]

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