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Correspondence
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Volume 333:324-325 August 3, 1995 Number 5
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Cholesterol Lowering and Coronary Vasomotion

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 by Anderson, T. J.
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To the Editor: Anderson et al. (Feb. 23 issue)1 suggest that the patients in their study obtained the most improvement in endothelium-dependent coronary vasomotion when treated with cholesterol-lowering therapy in combination with an antioxidant. The authors seem to be overinterpreting their findings.

It has previously been shown that dietary therapy has a favorable effect on endothelium-dependent vasorelaxation.2 It is disappointing that the compliance of the group that received dietary therapy alone was not monitored closely. It is unwise to dismiss an effect of diet without having the patients adhere to both the American Heart Association Step 1 and Step 2 . . . [Full Text of this Article]

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