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Previous Volume 333:364-368 August 10, 1995 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the decade since its initial description in the Journal,¹ Escherichia coli O157:H7 has emerged as a major cause of both sporadic cases and outbreaks of diarrhea in North America. The first report described outbreaks of gastrointestinal illness that were associated with the consumption of undercooked ground beef from a chain of fast-food restaurants. At the time, little was known about the pathophysiology, epidemiology, or clinical sequelae of infection with E. coli O157:H7. Since that report, several studies have shown that infection with E. coli O157:H7 is responsible for most cases of the hemolytic–uremic syndrome, which is a major cause . . . [Full Text of this Article]

Epidemiology

Incidence

Geographic and Seasonal Factors

Transmission

Pathophysiology and Immunity

Clinical Manifestations

Diagnosis

Treatment

Recognition of and Response to Outbreaks

Source Information

From the Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases (T.G.B., D.L.S., P.M.G.), and the Epidemic Intelligence Service, Epidemiology Program Office (T.G.B.), Centers for Disease Control and Prevention — both in Atlanta.

Address reprint requests to Dr. Boyce at the Centers for Disease Control and Prevention, Mailstop A-38, Atlanta, GA 30333.

References

Related Letters:

Escherichia coli O157:H7
Guerrant R. L., Theno D. M., Ryan M. J., Wall P. G., Cheasty T., Boyce T. G., Swerdlow D. L., Griffin P. M.
Extract | Full Text  
N Engl J Med 1995; 333:1711-1712, Dec 21, 1995. Correspondence

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