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Correspondence
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Volume 333:525-526 August 24, 1995 Number 8
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Saddle Nose

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 by Piette, J.-C.
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To the Editor: Three photographs of patients with relapsing polychondritis were recently published in the Journal's Images in Clinical Medicine series (March 2 issue),1 including a photograph of a patient with saddle nose. As shown in Figure 1, saddle nose can also be part of the clinical spectrum of Wegener's granulomatosis. In fact, the two diseases may have similar features of nasal and subglottic cartilaginous inflammation and collapse.2 When other clinical characteristics are not helpful in the differential diagnosis, it may be useful to search for serum antineutrophil cytoplasmic antibodies, which are quite specific markers for Wegener's granulomatosis.3


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