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Previous Volume 333:561-563 August 31, 1995 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Vaccination with bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, has been used extensively throughout the world as immunoprophylaxis against tuberculosis. Since 1976, intravesical administration of BCG has been used to treat superficial transitional-cell carcinoma of the bladder.¹ In both uses the complications of therapy have been rare, and the majority of serious side effects have occurred in immunocompromised persons.^2,3,4,5

In this report we describe two children with leukemia treated at our institution in whom BCG-associated meningitis developed. Neither child was receiving BCG as part of the immunotherapy for leukemia, and neither had a history of BCG vaccination. We . . . [Full Text of this Article]

Case Reports

Patient 1

Patient 2

Methods

Discussion

Source Information

From the Department of Pediatrics, Kaiser Permanente Medical Center, Woodland Hills, Calif. (M.M.S., S.K.S.); the Department of Pathology, Kaiser Permanente Regional Laboratories, North Hollywood, Calif. (A.M.V.); the Acute Communicable Disease Control Unit (C.P.) and the Tuberculosis Control Unit (A.T.N.), Los Angeles County Department of Health Services, Los Angeles; and the Center for Pulmonary Infectious Disease Control, University of Texas Health Center, Tyler (Y.Z.)

References

This article has been cited by other articles:

• (2007). Section 13 Cleaning procedures. J Oncol Pharm Pract 13: 55-61  
• Sander, P., Papavinasasundaram, K. G., Dick, T., Stavropoulos, E., Ellrott, K., Springer, B., Colston, M. J., Bottger, E. C. (2001). Mycobacterium bovis BCG recA Deletion Mutant Shows Increased Susceptibility to DNA-Damaging Agents but Wild-Type Survival in a Mouse Infection Model. Infect. Immun. 69: 3562-3568 [Abstract] [Full Text]