Of the approximately 2 million Americans with a diagnosis ofepilepsy who are treated with antiepileptic drugs, 20 percentcontinue to have seizures1; this group of patients accountsfor over 75 percent of the cost of epilepsy in the United States.2For many of those with medically refractory epilepsy, theirdisability can be completely eliminated by surgical intervention.Only a small percentage of potential surgical candidates, however,are currently referred to epilepsy-surgery centers.3
Overview
The classic 1886 paper of Victor Horsley4 heralded the modernera of epilepsy surgery, and the introduction of electroencephalography(EEG) in the first half of this . . . [Full Text of this Article]
Presurgical Evaluation
Early Intervention
Surgical Outcome
Future Directions
Source Information
From the Departments of Neurology and Neurobiology and the Brain Research Institute, UCLA School of Medicine, Los Angeles.
Address reprint requests to Dr. Engel at the Reed Neurological Research Ctr., 710 Westwood Plaza, Los Angeles, CA 90095-1769.
References
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