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Correspondence
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Volume 334:735-736 March 14, 1996 Number 11
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Noninvasive Ventilation for Exacerbations of Chronic Obstructive Pulmonary Disease

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 by Brochard, L.
To the Editor: The study by Brochard et al. (Sept. 28 issue)1 showed an impressive decrease in the need for endotracheal intubation in patients with acute exacerbations of chronic obstructive pulmonary disease treated with noninvasive positive-pressure ventilation (26 percent of whom required intubation), as compared with patients receiving standard therapy (74 percent of whom required intubation). We agree that noninvasive positive-pressure ventilation may be an important adjunct in managing exacerbations of chronic obstructive pulmonary disease, but several flaws in the study by Brochard et al. raise questions about the magnitude of the benefit of noninvasive positive-pressure ventilation, and thus about . . . [Full Text of this Article]

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