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A correction has been published: N Engl J Med 1996;335(2):143.

Review Article
Drug Therapy
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Volume 334:841-848 March 28, 1996 Number 13
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Inflammatory Bowel Disease
Stephen B. Hanauer, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In recent years there has been a series of advances in the treatment of inflammatory bowel disease (ulcerative colitis and Crohn's disease).1,2,3,4,5,6 Notwithstanding these advances, our understanding of inflammatory bowel disease7 has been hindered by the lack of representative animal models, an absence of pathognomonic features, and inadequate therapeutic end points. Sensitive or specific serologic or genetic markers of inflammatory bowel disease have yet to be identified.7 At present, the diagnosis of ulcerative colitis and Crohn's disease and the differentiation between them are based on nonspecific clinical and histologic patterns that are often obscured by intercurrent infectious or iatrogenic events8 . . . [Full Text of this Article]

Measurement of Disease Activity

Ulcerative Colitis

Crohn's Disease

Medical Therapy

Corticosteroids

Aminosalicylates

Immunomodulatory Drugs

            Azathioprine and Mercaptopurine

            Cyclosporine

            Methotrexate

Antibiotics

Nutritional Therapies

Supportive Therapy

Future Therapy

Conclusions


Source Information

From the University of Chicago Pritzker School of Medicine, Chicago.

Address reprint requests to Dr. Hanauer at the University of Chicago Medical Center, 5841 S. Maryland Ave., Chicago, Il 60637.

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