In recent years there has been a series of advances in the treatmentof inflammatory bowel disease (ulcerative colitis and Crohn'sdisease).1,2,3,4,5,6 Notwithstanding these advances, our understandingof inflammatory bowel disease7 has been hindered by the lackof representative animal models, an absence of pathognomonicfeatures, and inadequate therapeutic end points. Sensitive orspecific serologic or genetic markers of inflammatory boweldisease have yet to be identified.7 At present, the diagnosisof ulcerative colitis and Crohn's disease and the differentiationbetween them are based on nonspecific clinical and histologicpatterns that are often obscured by intercurrent infectiousor iatrogenic events8. . . [Full Text of this Article]
Measurement of Disease Activity
Ulcerative Colitis
Crohn's Disease
Medical Therapy
Corticosteroids
Aminosalicylates
Immunomodulatory Drugs
Azathioprine and Mercaptopurine
Cyclosporine
Methotrexate
Antibiotics
Nutritional Therapies
Supportive Therapy
Future Therapy
Conclusions
Source Information
From the University of Chicago Pritzker School of Medicine, Chicago.
Address reprint requests to Dr. Hanauer at the University of Chicago Medical Center, 5841 S. Maryland Ave., Chicago, Il 60637.
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