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Previous Volume 334:914-915 April 4, 1996 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The study of renal allografts has provided insight into the pathogenesis of renal diseases.¹ In patients with some disorders, such as Liddle's syndrome (in which long-standing hypertension may severely impair renal function), kidney transplantation cures the original disease, demonstrating that the distal tubular defect is intrinsic to the native kidney. In patients with other disorders, the original disease may recur in the graft. In patients with primary hyperoxaluria type I, the disease recurs because the metabolic defect in the liver persists, and in those with various glomerular diseases, the disease recurs because the triggering mechanism, which is often immunologic, is . . . [Full Text of this Article]

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