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Volume 334:1066 April 18, 1996 Number 16
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Genes, Blood, and Courage: A boy called Immortal Sword

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By David G. Nathan. 276 pp. Cambridge, Mass., Harvard University Press, 1995. $24.95. ISBN 0-674-34473-1.

In 1925 Thomas Cooley and Pearl Lee described five children in Detroit as having what was then called von Jacsch's anemia, as well as a "peculiar mongoloid appearance, caused by enlargement of the cranial and facial bones, combined with the skin coloration" (A Series of Cases of Splenomegaly in Children, with Anemia and Peculiar Bone Changes. Transactions of the American Pediatric Society 1925;37:29). This condition was first called thalassemia in 1932, by George Whipple, and it has been a focus of hematologic and genetic research in the second half of this century. The six-year-old protagonist of Genes, Blood, and Courage . . . [Full Text of this Article]




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