Infections with parasitic helminths and protozoa are importantcauses of morbidity and mortality worldwide. Chemotherapy hasan important role not only in the treatment of individual patientsbut also, in conjunction with public health and vector-controlmeasures, in reducing the transmission of parasitic infections.At present, however, there are no vaccines for human parasiticinfections, the scientific knowledge necessary to develop antiparasiticdrugs is rudimentary, and the mechanisms of action of most antiparasiticdrugs are poorly understood. Commercial incentives for the productionof drugs designed to fight infections that are mainly endemicin developing countries are limited, and some proved . . . [Full Text of this Article]
Anthelmintic Drugs
Albendazole
Echinococcosis
Intestinal Tapeworms and Cysticercosis
Intestinal Roundworms
Other Roundworms
Ivermectin
Onchocerciasis
Other Filariases
Other Roundworms
Ectoparasites
Praziquantel
Schistosomiasis
Other Flukes
Cestodes
Antiprotozoal Drugs
Albendazole
Giardiasis
Microsporidiosis
Fumagillin
Ocular Microsporidiosis
TrimethoprimSulfamethoxazole
Cyclosporiasis
Isosporiasis
Paromomycin
Cryptosporidiosis
Conclusions
Source Information
From the Department of Medicine, Harvard Medical School, and the Infectious Diseases Division, Beth Israel Hospital both in Boston.
Address reprint requests to Dr. Weller at Beth Israel Hospital, DA-617, 330 Brookline Ave., Boston, MA 02215.
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