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Previous Volume 334:1238-1248 May 9, 1996 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Lymphomas are the third most common group of cancers in children and adolescents in the United States, accounting for approximately 13 percent of newly diagnosed cancers in this age group.¹ Non-Hodgkin's lymphomas represent approximately 60 percent of these diagnoses, and Hodgkin's disease accounts for the remainder.^2,3 Approximately 500 cases of childhood non-Hodgkin's lymphoma occur annually in the United States.⁴

Non-Hodgkin's lymphomas are categorized as low, intermediate, or high grade on the basis of their clinical aggressiveness. Low- and intermediate-grade tumors predominate in adults, whereas more than 90 percent of children with non-Hodgkin's lymphoma have high-grade tumors. This difference is thought . . . [Full Text of this Article]

Epidemiology

Clinical Features

Diagnosis and Staging

Morphologic Features and Immunophenotype

Staging Studies and Prognostic Features

Molecular Features

Burkitt's Lymphoma

Lymphoblastic Lymphoma

Large-Cell Lymphoma

Treatment

Principles of Therapy

Limited-Stage Disease

Advanced-Stage Disease

Relapse

Future Directions

Source Information

From the Departments of Hematology–Oncology (J.T.S., W.M.C.), Pathology and Laboratory Medicine (J.R.D.), and Tumor Cell Biology (J.R.D.), St. Jude Children's Research Hospital, and the University of Tennessee College of Medicine — both in Memphis.

Address reprint requests to Dr. Sandlund at the Department of Hematology–Oncology, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105.

References

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