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Correspondence
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Volume 334:1270-1271 May 9, 1996 Number 19
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Parametric Models of Therapeutic Efficacy in Breast Cancer

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 by Henderson, I. C.
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To the Editor: We were intrigued by the editorial by Dr. Henderson entitled "Paradigmatic Shifts in the Management of Breast Cancer" (April 6, 1995, issue).1 Of particular interest are the questions he asks about the effect of adjuvant therapy: "Are some patients cured by adjuvant treatment whereas others derive no benefit at all? Or is the survival of most patients prolonged only transiently, with no patients or very few cured?"

Patients with breast cancer are eager to be shown the true balance sheet regarding adjuvant therapy. In return for a few months of toxic effects, is there an increase in . . . [Full Text of this Article]

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