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Previous Volume 334:113-114 January 11, 1996 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Reducing morbidity and mortality from coronary artery disease continues to be a major challenge. Many patients with coronary artery disease are asymptomatic or nearly so for long periods, and even when symptoms are present, their severity alone does not predict the outcome. Objective markers associated with an adverse outcome have been identified. They include exercise-induced electrocardiographic (ECG) changes and abnormalities on myocardial-perfusion scans and studies of ventricular wall motion. These abnormalities usually occur in the absence of symptoms but are related to myocardial ischemia — hence, the term "silent ischemia." It seems more appropriate, however, simply to use the term . . . [Full Text of this Article]

References

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• Bech, J., Madsen, J. K., Kelbaek, H. (1999). Amlodipine reduces myocardial ischaemia during exercise without compromising left ventricular function in patients with silent ischaemia: a randomised, double-blind, placebo-controlled study. Eur J Heart Fail 1: 395-400 [Abstract] [Full Text]  
• Pang, X., Alexacos, N., Letourneau, R., Seretakis, D., Gao, W., Boucher, W., Cochrane, D. E., Theoharides, T. C. (1998). A Neurotensin Receptor Antagonist Inhibits Acute Immobilization Stress-Induced Cardiac Mast Cell Degranulation, a Corticotropin-Releasing Hormone-Dependent Process. J. Pharmacol. Exp. Ther. 287: 307-314 [Abstract] [Full Text]  
• Deedwania, P. C., Carbajal, E. V. (1997). Can Ambulatory Monitoring Identify High-Risk Patients With Stable Coronary Artery Disease?. JAMA 277: 1760-1760 [Abstract]