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Previous Volume 334:119-122 January 11, 1996 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the recent report from the Nurses' Health Study about the relation between aspirin use and the risk of colorectal cancer (Sept. 7 issue),¹ a key question was whether the investigation inadvertently identified women who were resistant to colorectal cancer. A number of potentially confounding factors, including family history of colorectal cancer, smoking history, alcohol consumption, diet, and level of physical activity, were considered in the data analysis. Unaddressed was the effect of hormone-replacement therapy on the risk of colorectal cancer in the study population. Data from the Nurses' Health Study on hormone-replacement therapy and its relation . . . [Full Text of this Article]

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