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Correspondence
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Volume 334:1337-1339 May 16, 1996 Number 20
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Bacterial Vaginosis and Preterm Birth

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 by Hillier, S. L.
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To the Editor: The report by Hillier et al. on vaginal infections and preterm birth (Dec. 28 issue)1 adds conclusive weight to over a dozen descriptive studies linking bacterial vaginosis and prematurity. The comparatively modest 40 percent increase in the risk of preterm birth and low birth weight may have been due to the relatively late second-trimester enrollment. In contrast, Kurki et al. found that the risk of preterm birth was seven times higher among women in Helsinki, Finland, with bacterial vaginosis evaluated early in pregnancy.2 The relative absence of other risk factors for prematurity among these Finnish women highlights . . . [Full Text of this Article]

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