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Previous Volume 334:1396-1397 May 23, 1996 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Only in the past decade have well-conducted clinical trials advanced the treatment of congestive heart failure from palliation to prolongation of life. In 1986, the Veterans Administration Cooperative Vasodilator–Heart Failure Trial I (V-HeFT I) established the principle that medical therapy (with hydralazine plus nitrates) could prolong survival in patients with symptomatic heart failure.¹ On the heels of that study, angiotensin-converting–enzyme (ACE) inhibitors were definitively shown to improve survival in the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) and the Studies of Left Ventricular Dysfunction (SOLVD).^2,3 V-HeFT II then compared these therapies directly and showed that the survival benefit was greater . . . [Full Text of this Article]

References

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