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Molecular Medicine
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Volume 334:1526-1529 June 6, 1996 Number 23
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Adhesion Molecules— First of Two Parts

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-Related Article
 by Frenette, P. S.
-PubMed Citation
A diverse system of adhesion molecules and adhesion receptors participates in orchestrating vital biologic phenomena, such as embryogenesis, cell growth and differentiation, and wound repair. Over the past decade there has been immense progress in our understanding of adhesion molecules and their complex interactions. We review the main classes of adhesion receptors and give examples of diseases in which they have been found to be involved.

Among the many types of adhesion receptors on the cell surface, four major families stand out (Figure 1). The integrins are membrane glycoproteins with two subunits, designated {alpha} and {beta}. An important feature . . . [Full Text of this Article]


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From the Center for Blood Research and the Department of Pathology, Harvard Medical School, 800 Huntington Ave., Boston, MA 02115, where reprint requests should be addressed to Dr. Wagner.

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