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Previous Volume 334:1583-1590 June 13, 1996 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the past two years, three new antiepileptic drugs — gabapentin, lamotrigine, and felbamate — have been approved for use in the United States. They are the first such drugs to be approved since valproic acid, in 1978. These three drugs and others now in use in Europe, Canada, or Japan or being tested in trials in the United States reflect the resurgence of interest in developing new drugs for the treatment of epilepsy. This article reviews the pharmacologic characteristics of these new drugs, indications for their use, side effects, and appropriate regimens.

In many patients with epilepsy, seizures can . . . [Full Text of this Article]

Antiepileptic Drugs Recently Approved in the United States

Gabapentin

Lamotrigine

Felbamate

Antiepileptic Drugs Available in Europe, Canada, or Japan or Being Tested in the United States

Clobazam

Vigabatrin

Oxcarbazepine

Zonisamide

Tiagabine

Topiramate

Other New Antiepileptic Drugs

Current Recommendations for Use

Source Information

From the Department of Neurology, University of Pennsylvania, Philadelphia (M.A.D.), and the Epilepsy Research Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow, Scotland (M.J.B.).

Address reprint requests to Dr. Dichter at the Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104.

References

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