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A correction has been published: N Engl J Med 1997;336(10):739.

Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 334:1655-1662 June 20, 1996 Number 25
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Case 19-1996— Multisystem failure in a 33-year-old man after bone marrow transplantation
Kenneth B. Miller, and Fiona M. Graeme-Cook

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Presentation of Case

A 33-year-old man was admitted to the hospital for a bone marrow transplantation because of refractory acute myeloblastic leukemia, stage M1.

He had had proteinuria 18 years earlier, followed 3 years later by severe hypertension and increasing proteinuria, with a subsequent rise in the creatinine level. A renal biopsy revealed focal glomerulosclerosis. Extracorporeal hemodialysis was begun. Ten years before the current admission, a right nephrectomy was performed, and a cadaveric kidney, matched for one of four HLA-A and HLA-B categories, was transplanted into the right iliac fossa. Five and a half years before admission, nephrolithiasis was discovered in the renal . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnoses

Dr. Kenneth B. Miller's Diagnosis

Pathological Discussion

Anatomical Diagnoses

References




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