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Correspondence
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Volume 334:1669-1671 June 20, 1996 Number 25
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Intensity of Hemodialysis and Response to Erythropoietin

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 by Ifudu, O.
To the Editor: Ifudu et al. (Feb. 15 issue)1 state that decreasing blood urea nitrogen levels in patients receiving hemodialysis by a strategy of intensive dialysis improves the response to intravenous recombinant human erythropoietin. We congratulate the authors on this excellent piece of work. However, the observation that efficient dialysis improves physiologic and erythropoietin-stimulated erythropoiesis is not new. Charra et al. reported that lengthy dialysis (18 to 24 hours per week) was associated with a higher hematocrit and a higher survival rate than conventional dialysis (<12 hours per week).2

In their study, Ifudu et al. switched from a low-permeability, nonbiocompatible . . . [Full Text of this Article]

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