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Correspondence
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Volume 334:1749-1750 June 27, 1996 Number 26
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"Bouncing" Creatinine Levels

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To the Editor: We studied a series of unusual creatinine values in a 38-year-old man with end-stage cardiac disease and acute renal failure. The initial plasma creatinine levels ranged from 4.0 to 4.8 mg per deciliter and gradually decreased to 2.0 to 2.5 mg per deciliter over a period of several weeks. On multiple occasions, the level abruptly dropped to less than half of the preceding measurement, only to return to the previous value with the next sample. No clinical changes were associated with these events.

Routine creatinine analyses are done with a colorimetric method on a Hitachi 747 machine . . . [Full Text of this Article]

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