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Previous Volume 334:199 January 18, 1996 Number 3 Next

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By John Mendelsohn, Peter M. Howley, Mark A. Israel, and Lance A. Liotta. 574 pp., illustrated. Philadelphia, W.B. Saunders, 1995. $130. ISBN 0-7216-6483-0.

In The Molecular Basis of Cancer, the editors have undertaken the formidable task of presenting the state of the art of the rapidly changing field of molecular oncology. They have gathered an impressive array of well-known investigators and educators to contribute to this multiauthored textbook. The book is divided into four broad sections. The first, on the molecular basis of malignant transformation, focuses on the current understanding of the role of oncogene activation, signaling pathways, cell-cycle determinants, and tumor-suppressor genes in the expression of the malignant phenotype. The second section reviews the regulation of the growth and metastasis of malignant . . . [Full Text of this Article]

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