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Editorial
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Volume 334:265-267 January 25, 1996 Number 4
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Immunosuppression of Graves' Hyperthyroidism — Still an Elusive Goal

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Fifty years have passed since radioactive iodine and antithyroid drugs became available for the treatment of hyperthyroidism caused by Graves' disease. Despite the efficacy of both treatments, opinions still diverge widely as to which is better. A course of antithyroid-drug therapy requires prolonged daily treatment, but 40 to 50 percent of patients treated for a year remain euthyroid after therapy is discontinued. Therapy with iodine-131, on the other hand, is simple and fast (one dose usually suffices), but the treatment causes hypothyroidism in a large proportion of patients. In a survey of endocrinologists, 69 percent of the responding physicians in . . . [Full Text of this Article]

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