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Correspondence
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Volume 334:535-537 February 22, 1996 Number 8
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Cocaine-Associated Myocardial Ischemia

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 by Hollander, J. E.
To the Editor: The review article (Nov. 9 issue)1 by Dr. Hollander entitled "The Management of Cocaine-Associated Myocardial Ischemia" needs some clarification. First, it suggests that cocaine blocks the "reuptake of . . . excitatory amino acids" in addition to its well-established inhibitory effect on the reuptake of catecholamines. Are there any published studies demonstrating the inhibitory effect of cocaine on the reuptake of excitatory amino acids? Obviously, this would be an extremely important finding with drastic pathophysiologic and therapeutic implications. Is the suggested inhibitory effect of cocaine on the reuptake of excitatory amino acids the author's personal observation, or . . . [Full Text of this Article]

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