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Volume 335:821 September 12, 1996 Number 11
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Case 11-1996: Atheroembolism of the Kidneys and Lungs

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 by Stanton, R.C.
To the Editor: In the clinical discussion of Case 11-1996 (April 11 issue),1 no mention was made of the possible role of anticoagulation in the patient's progressive illness. The patient had chronic renal insufficiency with marked proteinuria. Three months before admission, transient weakness developed in his right arm, and evaluation revealed a small atheromatous plaque at the right carotid bifurcation. Treatment with warfarin was begun. Progressive renal failure and pulmonary edema subsequently developed, and then hemoptysis. A renal biopsy revealed cholesterol microembolization as the cause of the renal failure. Open-lung biopsy also revealed atheromatous emboli in the pulmonary arteries.

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