Pain from cancer is a major health care problem.1,2,3 Thirtypercent of patients with cancer have pain at the time of diagnosis,and 65 to 85 percent have pain when their disease is advanced.2,4,5,6The impact of cancer pain is magnified by the interaction ofpain and its treatments with other common cancer symptoms: fatigue,weakness, dyspnea, nausea, constipation, and impaired cognition.4,6Cancer pain can be effectively treated in 85 to 95 percent ofpatients with an integrated program of systemic, pharmacologic,and anticancer therapy.7,8 Many of the remaining patients canbe helped by the appropriate use of invasive procedures.9,10,11. . . [Full Text of this Article]
Selection of the Appropriate Analgesic Therapy
Appropriate Analgesic Dosage
Route of Administration of Analgesic Drugs
Appropriate Intervals of Analgesic Dosing
Prevention of Persistent Pain and Relief of Breakthrough Pain
Titration of Analgesic-Drug Doses
Side Effects of Analgesic Drugs
Sequential Trials of Analgesic Drugs
Adjuvant Therapy
Conclusions
Source Information
From the Fox Chase Cancer Center, 7701 Burholme Ave., Philadelphia, PA 19111, where reprint requests should be addressed to Dr. Levy.
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