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Correspondence
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Volume 335:1240 October 17, 1996 Number 16
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Sequencing of Chemotherapy and Radiotherapy in Breast Cancer

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To the Editor: Recht et al. (May 23 issue)1 describe the effect of sequencing of chemotherapy and radiation on the risk of relapse and death in 244 women with early-stage breast cancer. Two points need to be made. First, distant metastases developed in two patients in the radiotherapy-first group while they were receiving therapy. The authors do not state what staging procedures were done before enrollment in the study. Perhaps the authors could recalculate their statistics with these two patients excluded from the analysis, to see whether the two groups still differed from each other. The second point is that . . . [Full Text of this Article]

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