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Previous Volume 335:1309-1310 October 24, 1996 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Angiogenesis, the process of new capillary development, is normally controlled, limited, and dependent on a balance between stimulatory and inhibitory factors. In men, wound healing is the only physiologic example of this process after birth, whereas in women angiogenesis is also necessary for ovulation, the formation of the corpus luteum, and placental development.

Angiogenesis is an essential feature of many diseases, among which are cancers, various retinopathies, rheumatoid arthritis, psoriasis, and atherosclerosis.¹ In these pathologic states, the balance between stimulatory and inhibitory factors favors persistent capillary growth. We can view Kaposi's sarcoma, with its abundant slit-like vascular spaces, proliferating spindle . . . [Full Text of this Article]

References

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• Malatos, S., Neubert, H., Kicman, A. T., Iles, R. K. (2005). Identification of Placental Transforming Growth Factor-{beta} and Bikunin Metabolites as Contaminants of Pharmaceutical Human Chorionic Gonadotrophin Preparations by Proteomic Techniques. Mol. Cell. Proteomics 4: 984-992 [Abstract] [Full Text]  
• Butler, S. A., Iles, R. K. (2003). Ectopic Human Chorionic Gonadotropin {beta} Secretion by Epithelial Tumors and Human Chorionic Gonadotropin {beta}-Induced Apoptosis in Kaposi's Sarcoma: Is There a Connection?. Clin. Cancer Res. 9: 4666-4673 [Abstract] [Full Text]  
• Antman, K., Chang, Y. (2000). Kaposi's Sarcoma. NEJM 342: 1027-1038 [Full Text]  
• Harris, P. J., Russo, I. H., Grulich, A. E., Kaldor, J. M., Gill, P. S., Lunardi-Iskandar, Y., Gallo, R. C., Krown, S. E., Rabkin, C. S. (1997). Intralesional Human Chorionic Gonadotropin for Kaposi's Sarcoma. NEJM 336: 1187-1189 [Full Text]