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Clinical Debate
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Volume 335:1311-1312 October 24, 1996 Number 17
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Should Thrombolysis or Primary Angioplasty Be the Treatment of Choice for Acute Myocardial Infarction?

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In a community-based study reported in this issue of the Journal, Every et al. compared the benefits of thrombolytic therapy with those of primary coronary angioplasty for acute myocardial infarction. Although earlier trials had suggested that primary angioplasty may be superior, Every et al. found the two approaches essentially equivalent. How should physicians choose between them?

We solicited two opposing opinions, along with rebuttals, which we present in the first of a new series of occasional pieces called Clinical Debate. Lange and Hillis argue that thrombolytic therapy should be the initial therapy, whereas Grines favors coronary angioplasty. Is there . . . [Full Text of this Article]

Address reprint requests to Dr. Lange at Rm. CS7.102, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75235-9047.

Address reprint requests to Dr. Grines at the Division of Cardiology, William Beaumont Hospital, 3601 W. 13 Mile Rd., Royal Oak, MI 48073-6769.


Related Letters:

Thrombolysis or Primary Angioplasty for Acute Myocardial Infarction?
Zijlstra F., Hoorntje J. C.A., de Boer M.-J., Magalski A., O'Keefe J. H., Leff B., Lange R. A., Hillis L. D., Grines C. L.
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N Engl J Med 1997; 336:1101-1103, Apr 10, 1997. Correspondence

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