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Previous Volume 335:1397-1398 October 31, 1996 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The study by Belluzzi et al. (June 13 issue)¹ suggests that fish oil reduced the frequency of relapse in patients with Crohn's disease. However, there is a serious flaw in the design of this study: the placebo group received a mixture of caprylic and capric acids. These saturated medium-chain fatty acids may not be an appropriate placebo. There is epidemiologic and experimental evidence that fatty acids, such as those contained in vegetable oils and fats, may have a role in the causation and pathogenesis of Crohn's disease.^2,3 It is likely that the fatty acids given as placebo . . . [Full Text of this Article]

References

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