FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 335:108-114 July 11, 1996 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Purchase this article Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Venous thromboembolism is an uncommon but leading cause of illness and death during pregnancy and the puerperium.^1,2 It has been reported to occur in 1 in 1000 to 1 in 2000 pregnancies,^3,4 although few studies have used objective diagnostic techniques. Over the past two decades, there has been considerable change in the management of venous thromboembolism in nonpregnant patients. Moreover, our understanding of changes in the coagulation system during pregnancy has increased. However, the management of venous thromboembolism during pregnancy remains a subject of controversy because of the lack of prospective clinical trials. In this article, we will summarize our . . . [Full Text of this Article]

Pathophysiology

Diagnosis

Deep-Vein Thrombosis

Pulmonary Embolism

Management

Antepartum Venous Thromboembolism

Labor and Delivery

Postpartum Venous Thromboembolism

Complications of Treatment

Prophylaxis

Conclusions

Source Information

From the Department of Obstetrics, Gynecology, and Reproductive Medicine, State University of New York at Stony Brook (M.R.T.); and the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor (J.G.W.).

Address reprint requests to Dr. Toglia at the Department of Obstetrics, Gynecology, and Reproductive Medicine, Health Sciences Center T9, Room 033, State University of New York at Stony Brook, Stony Brook, NY 11794-8091.

References

Related Letters:

Venous Thromboembolism during Pregnancy
Shibolet O., Schwaber M. J., Brezis M., Sandison A. J.P., Panayiotopoulos Y. P., Taylor P. R., Lockshin M. D., Toglia M. R., Weg J. G.
Extract | Full Text  
N Engl J Med 1996; 335:1846-1847, Dec 12, 1996. Correspondence

This article has been cited by other articles:

• Pahade, J. K., Litmanovich, D., Pedrosa, I., Romero, J., Bankier, A. A., Boiselle, P. M. (2009). Quality Initiatives@;DELIM@;Continuing Medical Education: Imaging Pregnant Patients with Suspected Pulmonary Embolism: What the Radiologist Needs to Know1. RadioGraphics 29: 639-654 [Abstract] [Full Text]  
• Pahade, J. K., Litmanovich, D., Pedrosa, I., Romero, J., Bankier, A. A., Boiselle, P. M. (2009). Quality Initiatives: Imaging Pregnant Patients with Suspected Pulmonary Embolism: What the Radiologist Needs to Know. RadioGraphics 0: 293085226- [Abstract] [Full Text]  
• Mahmood, T. A (2009). Review: Obesity and pregnancy: an obstetrician's view. British Journal of Diabetes & Vascular Disease 9: 19-22 [Abstract]  
• Nelson, S. M., Greer, I. A. (2008). The potential role of heparin in assisted conception. Hum Reprod Update 14: 623-645 [Abstract] [Full Text]  
• Authors/Task Force Members, , Torbicki, A., Perrier, A., Konstantinides, S., Agnelli, G., Galie, N., Pruszczyk, P., Bengel, F., Brady, A. J.B., Ferreira, D., Janssens, U., Klepetko, W., Mayer, E., Remy-Jardin, M., Bassand, J.-P., ESC Committee for Practice Guidelines (CPG), , Vahanian, A., Camm, J., De Caterina, R., Dean, V., Dickstein, K., Filippatos, G., Funck-Brentano, C., Hellemans, I., Kristensen, S. D., McGregor, K., Sechtem, U., Silber, S., Tendera, M., Widimsky, P., Zamorano, J. L., Document Reviewers, , Zamorano, J.-L., Andreotti, F., Ascherman, M., Athanassopoulos, G., De Sutter, J., Fitzmaurice, D., Forster, T., Heras, M., Jondeau, G., Kjeldsen, K., Knuuti, J., Lang, I., Lenzen, M., Lopez-Sendon, J., Nihoyannopoulos, P., Perez Isla, L., Schwehr, U., Torraca, L., Vachiery, J.-L. (2008). Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J 29: 2276-2315 [Full Text]  
• Drenthen, W., Pieper, P. G., Roos-Hesselink, J. W., van Lottum, W. A., Voors, A. A., Mulder, B. J.M., van Dijk, A. P.J., Vliegen, H. W., Yap, S. C., Moons, P., Ebels, T., van Veldhuisen, D. J., on behalf of the ZAHARA Investigators, (2007). Outcome of Pregnancy in Women With Congenital Heart Disease: A Literature Review. J Am Coll Cardiol 49: 2303-2311 [Abstract] [Full Text]  
• Gomez-Puerta, J. A, Cervera, R., Espinosa, G., Asherson, R. A, Garcia-Carrasco, M., da Costa, I. P, Andrade, D. C O, Borba, E. F, Makatsaria, A., Bucciarelli, S., Ramos-Casals, M., Font, J., for the Catastrophic Antiphospholipid Syndrome Reg, (2007). Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases. Ann Rheum Dis 66: 740-746 [Abstract] [Full Text]  
• van Stralen, K J, Terveer, E M, Doggen, C J M, Helmerhorst, F M, Vandenbroucke, J P (2007). The tortuous history of the implementation of early ambulation after delivery. JRSM 100: 90-96 [Full Text]  
• Dhar, J. P., Sokol, R. J. (2006). Lupus and Pregnancy: Complex Yet Manageable. Clin Med Res 4: 310-321 [Abstract] [Full Text]  
• Drenthen, W, Pieper, P G, Roos-Hesselink, J W, Schmidt, A C M, Mulder, B J M, van Dijk, A P J, Vliegen, H W, Sollie, K M, Voors, A A, Ebels, T, van Veldhuisen, D J, on behalf of the ZAHARA investigators, (2006). Non-cardiac complications during pregnancy in women with isolated congenital pulmonary valvar stenosis. Heart 92: 1838-1843 [Abstract] [Full Text]  
• Yousefzadeh, D. K., Ward, M. B., Reft, C. (2006). Internal Barium Shielding to Minimize Fetal Irradiation in Spiral Chest CT: A Phantom Simulation Experiment.. Radiology 239: 751-758 [Abstract] [Full Text]  
• Rao, A. K., Chitkara, U., Milki, A. A. (2005). Subclavian vein thrombosis following IVF and ovarian hyperstimulation: a case report. Hum Reprod 20: 3307-3312 [Abstract] [Full Text]  
• Schuster, M. E., Fishman, J. E., Copeland, J. F., Hatabu, H., Boiselle, P. M. (2003). Pulmonary Embolism in Pregnant Patients: A Survey of Practices and Policies for CT Pulmonary Angiography. Am. J. Roentgenol. 181: 1495-1498 [Abstract] [Full Text]  
• Deitcher, S. R, Gomes, M. P. (2003). Hypercoagulable state testing and malignancy screening following venous thromboembolic events. Vasc Med 8: 33-46 [Abstract]  
• Joffe, H. V., Goldhaber, S. Z. (2002). Upper-Extremity Deep Vein Thrombosis. Circulation 106: 1874-1880 [Full Text]  
• Winer-Muram, H. T., Boone, J. M., Brown, H. L., Jennings, S. G., Mabie, W. C., Lombardo, G. T. (2002). Pulmonary Embolism in Pregnant Patients: Fetal Radiation Dose with Helical CT. Radiology 224: 487-492 [Abstract] [Full Text]  
• Soomro, R.M., Bucur, I.J., Noorani, S. (2002). Cumulative Incidence of Venous Thromboembolism During Pregnancy and Puerperium: A Hospital-Based Study. ANGIOLOGY 53: 429-434 [Abstract]  
• Wallaschofski, H., Donne, M., Eigenthaler, M., Hentschel, B., Faber, R., Stepan, H., Koksch, M., Lohmann, T. (2001). PRL as a Novel Potent Cofactor for Platelet Aggregation. J. Clin. Endocrinol. Metab. 86: 5912-5919 [Abstract] [Full Text]  
• Dragoni, F., Tormene, D., Simioni, P., Arcieri, P., Avvisati, G., Girolami, A. (2001). ProC Global: A New Automated Screening Assay for the Evaluation of Total Function of the Protein C System. CLIN APPL THROMB HEMOST 7: 351-355 [Abstract]  
• Ginsberg, J. A., Crowther, M. A., White, R. H., Ortel, T. L. (2001). Anticoagulation Therapy. ASH Education Book 2001: 339-357 [Abstract] [Full Text]  
• van Driel, D., Wesseling, J., Sauer, P. J. J., van der Veer, E., Touwen, B. C. L., Smrkovsky, M. (2001). In Utero Exposure to Coumarins and Cognition at 8 to 14 Years Old. Pediatrics 107: 123-129 [Abstract] [Full Text]  
• Hyers, T. M., Agnelli, G., Hull, R. D., Morris, T. A., Samama, M., Tapson, V., Weg, J. G. (2001). Antithrombotic Therapy for Venous Thromboembolic Disease. Chest 119 : 176S-193S [Full Text]  
• Bhatia, P, Bhatia, K (2000). Pregnancy and the lungs. Postgrad. Med. J. 76: 683-689 [Full Text]  
• (2000). Guidelines on diagnosis and management of acute pulmonary embolism. Eur Heart J 21: 1301-1336  
• Walker, I. D (2000). Thrombophilia in pregnancy. J. Clin. Pathol. 53: 573-580 [Abstract] [Full Text]  
• de Swiet, M. (1999). Review Article: Management of pulmonary embolus in pregnancy. Eur Heart J 20: 1378-1385  
• (1999). Low Molecular Weight Heparin as Thromboprophylaxis Throughout Pregnancy in Heritable Thrombophilic Women. CLIN APPL THROMB HEMOST 5: 198-199  
• Goldhaber, S. Z. (1998). Pulmonary Embolism. NEJM 339: 93-104 [Full Text]  
• Noel, A. A., Pappas, P. J., Haser, P. B., Silva, M. B. JR, Hobson, R. W. (1998). Experience with Greenfield Filters in Pregnant Women for Deep Venous Thrombosis and Pulmonary Embolism Case Reports. VASC ENDOVASCULAR SURG 32: 367-372 [Abstract]  
• Goldhaber, S. Z (1998). Clinical overview of venous thromboembolism. Vasc Med 3: 35-40 [Abstract]  
• Meaney, J. F.M., Weg, J. G., Chenevert, T. L., Stafford-Johnson, D., Hamilton, B. H., Prince, M. R. (1997). Diagnosis of Pulmonary Embolism with Magnetic Resonance Angiography. NEJM 336: 1422-1427 [Abstract] [Full Text]  
• Shibolet, O., Schwaber, M. J., Brezis, M., Sandison, A. J.P., Panayiotopoulos, Y. P., Taylor, P. R., Lockshin, M. D., Toglia, M. R., Weg, J. G. (1996). Venous Thromboembolism during Pregnancy. NEJM 335: 1846-1847 [Full Text]  
• Vandenbroucke, J. P, van der Meer, F. J M, Helmerhorst, F. M, Rosendaal, F. R (1996). Factor V Leiden: should we screen oral contraceptive users and pregnant women?. BMJ 313: 1127-1130 [Full Text]