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Images in Clinical Medicine
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Volume 335:1569 November 21, 1996 Number 21
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Sister Joseph's Node in Non-Hodgkin's Lymphoma

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Figure 1A.



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Figure 1. A 44-year-old man was found to have an umbilical tumor. Examination revealed the lesion to be firm and subcutaneous, approximately 5 cm in diameter, with erythema around the navel. The cervical and inguinal lymph nodes were enlarged. Computed tomography revealed an umbilical mass measuring 4.5 cm by 3.5 cm (Panel A, arrow) and multiple enlarged lymph nodes in the pelvis. A skin-biopsy specimen showed massive infiltration of the dermis by medium-sized, atypical lymphoid cells, which infiltrated between the bundles of collagen (Panel B; hematoxylin and eosin, x200). Cells similar to those of the Sister Joseph's node . . . [Full Text of this Article]

 



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