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Previous Volume 335:1749-1754 December 5, 1996 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Currently, there are 50,000 to 75,000 girls and women with Turner's syndrome in the United States alone. Turner's syndrome, first described in 1938,¹ is the most common sex-chromosome abnormality in females, affecting an estimated 3 percent of all females conceived. However, the frequency among live-born female infants is only 1 in 1500 to 1 in 2500, and as many as 15 percent of spontaneous miscarriages have a 45,X karyotype. It is estimated that only 1 in 100 embryos with a 45,X karyotype survive to term.² Molecular studies have shown that the maternal X is retained in two thirds of patients . . . [Full Text of this Article]

Prenatal Management

Care of Infants and Children

Care of Adults

Fertility and Family Planning

Psychological and Educational Issues

Source Information

From the Division of Pediatric Endocrinology, Albert Einstein College of Medicine–Montefiore Medical Center, 111 E. 210th St., Bronx, NY 10467, where reprint requests should be addressed to Dr. Saenger.

References

Related Letters:

Turner's Syndrome
Gargan T. J., Peerzada J. M., Rozycki A. A., Nordgren R. E., Taback S. P., Deal C., Van Vliet G., Saenger P.
Extract | Full Text  
N Engl J Med 1997; 336:1526-1528, May 22, 1997. Correspondence

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