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Images in Clinical Medicine
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Volume 335:1815 December 12, 1996 Number 24
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Hemochromatosis

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A 62-year-old woman who was euthyroid while taking levothyroxine for radioactive iodine–induced hypothyroidism was noted to have trophic changes in her fingernails. The physical examination was otherwise normal. During a search for subclinical iron deficiency, her serum ferritin concentration was found to be 3583 ng per milliliter (normal range, 30 to 300). The only abnormality on liver-function testing was an aspartate aminotransferase concentration of 39 U per liter (normal range, 0 to 30). A liver biopsy showed deposition of iron in the hepatocytes with sparing of Kupffer's cells and mild chronic inflammation in the portal triads. The hepatic-tissue iron concentration . . . [Full Text of this Article]

 

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