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Previous Volume 335:1845-1846 December 12, 1996 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The report by Walters et al. on successful eradication of sickle cell disease through bone marrow transplantation (Aug. 8 issue)¹ raises some ethical issues. Although this multicenter study was conducted under the supervision of a Data Safety and Monitoring Board of the National Institutes of Health and had the approval of each center's institutional review board, the article raises questions about the issues of informed consent. The following statement from the methods section is confusing: "All the patients or their parents or guardians gave written informed consent for their participation." The study involved only children under 16 . . . [Full Text of this Article]

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