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Editorial
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Volume 335:278-280 July 25, 1996 Number 4
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Helicobacter pylori in the Stomach — A Paradox Unmasked

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In 1993, a National Institutes of Health Consensus Conference declared infection with Helicobacter pylori to be an important cause of duodenal and gastric ulcers.1 Soon thereafter, the International Agency for Research on Cancer classified H. pylori as a group 1 carcinogen, a definite cause of gastric adenocarcinoma in humans.2 In this issue of the Journal, Hansson and colleagues report that patients with duodenal ulcers have a decreased risk of gastric cancer, whereas those with gastric ulcers have an increased risk.3 Thus, a paradox in the epidemiology of gastric disease is unmasked. The incidence of gastric cancer correlates positively with the . . . [Full Text of this Article]

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Related Letters:

Helicobacter pylori, Gastric Ulcer, and Duodenal Ulcer
Mitchell H. M., Hazell S. L., Rubin C. E., Graham J. R., Parsonnet J., Kuipers E. J., Meuwissen S. G.M., Havu N.
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N Engl J Med 1996; 335:1841-1843, Dec 12, 1996. Correspondence

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