In 1993, a National Institutes of Health Consensus Conferencedeclared infection with Helicobacter pylori to be an importantcause of duodenal and gastric ulcers.1 Soon thereafter, theInternational Agency for Research on Cancer classified H. pylorias a group 1 carcinogen, a definite cause of gastric adenocarcinomain humans.2 In this issue of the Journal, Hansson and colleaguesreport that patients with duodenal ulcers have a decreased riskof gastric cancer, whereas those with gastric ulcers have anincreased risk.3 Thus, a paradox in the epidemiology of gastricdisease is unmasked. The incidence of gastric cancer correlatespositively with the . . . [Full Text of this Article]
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