To the Editor: Bhatia et al. (March 21 issue)1 make the unwarrantedstatement that radiation, but not chemotherapy, increases therisk of solid tumors, especially breast tumors, in patientstreated for childhood Hodgkin's disease.
In the study cohort, only 8 percent of the patients receivedchemotherapy alone; 23 percent received radiation alone. Theremainder received both, but to compare the risks of treatments,only the patients receiving one or the other are appropriatefor the analysis. Only one patient in the group receiving chemotherapyalone had a solid tumor, but since the expected number of caseswas less than one, . . . [Full Text of this Article]
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