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Previous Volume 335:509-510 August 15, 1996 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the Western world the incidence of adenocarcinoma of the esophagus has risen markedly in the past three decades. Barrett's specialized columnar-cell metaplasia (Barrett's esophagus), which is the most important predisposing factor, is found in more than 80 percent of patients with adenocarcinoma of the distal esophagus.¹ Although recent studies indicate that microscopic areas of metaplasia may also occur in true carcinoma of the cardia and subcardial carcinoma,² the etiology, epidemiology, and pathology of these tumors appear to differ from those of adenocarcinoma of the esophagus.³ Adenocarcinoma of the distal esophagus often grows submucosally toward the proximal esophagus and spreads . . . [Full Text of this Article]

References

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Multimodal Therapy for Esophageal Adenocarcinoma
Badwe R. A., Vaidya J. S., Bhansali M. S., Gaffney P., Funk E. M., Witte J., Walsh T. N., Kelly A., Hennessy T. P.J.
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N Engl J Med 1997; 336:374-376, Jan 30, 1997. Correspondence

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